Lyme disease is a debilitating, sometimes fatal infection passed to humans by infected blacklegged ticks. According to the Centers for Disease Control and Prevention, there are more than 30,000 cases of the disease each year nationwide. Due to underreporting, the actual incidence may be as high as 10 times the reported figure.
About 86% of confirmed cases of Lyme disease in the United States were reported in the 12 states on this list -- which are largely concentrated in the Northeast and mid-Atlantic regions. Almost anyone who spends time outdoors -- whether in backyards, gardens, forests, or hiking trails -- is at risk of getting bitten by an infected tick. States with higher rates of Lyme disease often have more physically active adult populations and relatively large rural populations.
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